Puerarin reduces ischemia/reperfusioninduced myocardial injury in diabetic rats via


Puerarin—an isoflavone with beneficial effects on bone health

Puerarin, also called daidzein-8-c-glucoside (7,4'-dihydroxy-8-c-glycosylisoflavone), is an isoflavone compound isolated from Pueraria lobata (Fig. 1).As one of the important flavonoids, puerarin has unique physicochemical properties [33].Due to the stereo-hindrance of C-cyclopyranyl group, puerarin molecules easily form large conjugate systems, which tend to be flat in space, and thus, its.


Puerarine in China, Puerarine Manufacturers & Suppliers in China

Puerarin, a chemotaxonomic marker of Pueraria, received investigational drug status for the treatment of alcohol abuse and listed in DRUGBANK database. The purpose of this review is to provide insights on health benefits of Pueraria, its bioactive constituents and molecular mechanisms. The information is retrieved from various databases.


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Puerarin is an isoflavone compound derived from Pueraria lobata in traditional Chinese medicine. Accumulating evidence has indicated that puerarin demonstrates multiple pharmacological effects and exhibits treatment potential for various neurological disorders. Based on the latest research progress.


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The antihyperglycemic action of puerarin, purified from the roots of Pueraria lobata, was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Bolus intravenous injection of puerarin decreased the plasma glucose concentrations in a dose-dependent manner in STZ-diabetic rats. Similar treatment with puerarin also decreased.


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Puerarin is an isoflavone compound extracted from the root of Pueraria lobata and has pharmacological effects such as dilating cerebral vessels and anti-free radical generation in cerebral ischemic tissues. With the deepening of experimental research and clinical research on puerarin, it has been found that puerarin has a protective effect on.


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Puerarin, an isoflavone glycoside derived from Pueraria lobata (Willd.) Ohwi, has been identified as a pharmacologically active component with diverse benefits. A large number of experimental and clinical studies have demonstrated that puerarin is widely used in the treatment of a variety of diseases. Among them, cardiovascular diseases (CVDs.


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Puerarin is a C-glucoside of the isoflavone daidzein extracted from Pueraria. It has been widely investigated to explore its therapeutic role in eye diseases and the molecular mechanisms. Purpose: To collect the available literature from 2000 to 2022 on puerarin in the treatment of ocular diseases and suggest the future required directions to.


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Puerarin has shown unique pharmacological effects on myocardial ischemia (MI). Changing the crystal form is an effective approach to improve the cardioprotective effects of puerarin. However, the.


Puerarin reduces ischemia/reperfusioninduced myocardial injury in diabetic rats via

Puerarin has various effects such as vasodilation, cardioprotection, neuroprotection, antioxidant, anticancer, anti-inflammation, alleviating pain, promoting bone formation, inhibiting alcohol.


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Up to now, puerarin has been widely proven to have pharmacological activities such as vasodilator, anti-inflammatory, antioxidant, anti-apoptotic, regulating autophagy, anti-insulin resistance, anti-cancer, etc. It has protective effects on cell damage caused by pathological factors and has shown good efficacy in the treatment of various diseases (Ma et al., 2022).


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Puerarin is mainly used to treat eye diseases by ocular administration and systemic administration. Puerarin has poor water and lipid solubility. Its solubility in water is 0.46 mg/ml, and in phosphate buffer at pH 7.4 is 7.56 mg/ml. Therefore, puerarin has poor oral absorption and low bioavailability.


الرعاية الصحية Puerarin Kudzu الجذر استخراج مسحوق العشبية

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2.1. Obesity, metabolic syndrome, and diabetes mellitus. Obesity, metabolic syndrome, and diabetes mellitus are major risk factors for the initiation and progression of cardiovascular and cerebrovascular diseases and are dramatically increased with advancing age in modern society. 12 In obese mice treated with puerarin for 8 months, circulating levels of isoflavone metabolites were.


Puerarin

Puerarin derivative P1-EA and P2-EA were formed by substitution of the original phenolic hydroxyl in the puerarin molecules, which had higher lipophilicity and thus better permeabilized through the blood-brain barrier as compared to puerarin. It was resulted in an enhancement of protective activity against cerebral ischemic damage in a mouse.


Pueraria mirifica extract / puerarin

Pemberian obat racikan atau disebut puyer berisiko baik dari segi ketepatan dosis, efektivitas biaya, maupun efisiensi waktu. Peracikan obat umumnya bertujuan untuk membantu pasien mendapatkan obat yang tidak mudah ditemukan di pasaran. Pola peracikan obat di apotek maupun farmasi rumah sakit telah jauh berubah dalam beberapa dekade terakhir.


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1. Introduction. Puerarin is the main active constituent isolated from the root of the Pueraria lobata (Willd.)Ohwi (Fabaceae), which is native to Southeast Asia and widely known as Gegen in traditional Chinese medicine. As one of the earliest known Chinese medicinal herbs in China, Gegen is frequently used to treat a wide range of conditions including fever, pain, diabetes, gastrointestinal.

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